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16-bit Microcontrollers - MCU

16-bit Microcontrollers are in stock with same-day shipping at Mouser from industry leading manufacturers. Mouser is an authorized distributor for many 16-bit microcontroller manufacturers including Infineon, Microchip, NXP, Renesas, Texas Instruments & more.
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Please view our large selection of 16-bit microcontrollers below.

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Part #

16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 128KB Flash, 50MHz, -40/+105degC, Automotive Qualified, QFP 112

S912XEG128W1MAL
NXP Semiconductors
1: $25.72
300In Stock

Mfr. Part #
S912XEG128W1MAL

Mouser Part #
841-S912XEG128W1MAL

NXP Semiconductors

16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 128KB Flash, 50MHz, -40/+105degC, Automotive Qualified, QFP 112

Datasheet

300In Stock

$25.72

$20.59

$19.31

$16.75

View

Min.: 1
Mult.: 1

HCS12X

128 kB

12 kB

LQFP-112

50 MHz

2 x 8 bit/10 bit/12 bit

91 I/O

1.72 V

1.98 V

SMD/SMT

16 bit

- 40 C

+ 125 C

S12XE

AEC-Q100

Tray

16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 256KB Flash, 50MHz, -40/+125degC, Automotive Qualified, QFP 144

S912XET256W1MAG
NXP Semiconductors
1: $27.24
236In Stock

Mfr. Part #
S912XET256W1MAG

Mouser Part #
841-S912XET256W1MAG

NXP Semiconductors

16-bit Microcontrollers - MCU 16-bit MCU, S12X core, 256KB Flash, 50MHz, -40/+125degC, Automotive Qualified, QFP 144

Datasheet

236In Stock

$27.24

$21.92

$20.59

$18.28

View

Min.: 1
Mult.: 1

HCS12X

256 kB

16 kB

LQFP-144

50 MHz

2 x 8 bit/10 bit/12 bit

119 I/O

1.98 V

1.72 V

SMD/SMT

16 bit

- 40 C

+ 125 C

S12XE

AEC-Q100

Tray

16-bit Microcontrollers - MCU MagniV 16-bit MCU, S12Z core, 192KB Flash, 32MHz, -40/+125degC, Automotive Qualified, QFP 64

S912ZVCA19F0MKH
NXP Semiconductors
1: $10.06
630In Stock

Mfr. Part #
S912ZVCA19F0MKH

Mouser Part #
841-S912ZVCA19F0MKH

NXP Semiconductors

16-bit Microcontrollers - MCU MagniV 16-bit MCU, S12Z core, 192KB Flash, 32MHz, -40/+125degC, Automotive Qualified, QFP 64

Learn More

Datasheet

630In Stock

$10.06

$7.84

$7.28

$6.67

View

Min.: 1
Mult.: 1

S12Z

190 kB

8 kB

LQFP-64

32 MHz

12 bit

42 I/O

5.5 V

18 V

SMD/SMT

16 bit

- 40 C

+ 125 C

S12ZVC

AEC-Q100

Tray

16-bit Microcontrollers - MCU MagniV 16-bit MCU, S12Z core, 64KB Flash, 32MHz, -40/+85degC, Automotive Qualified, QFP 144

S912ZVHY64F1CLQ
NXP Semiconductors
1: $16.34
300In Stock

Mfr. Part #
S912ZVHY64F1CLQ

Mouser Part #
841-S912ZVHY64F1CLQ

NXP Semiconductors

16-bit Microcontrollers - MCU MagniV 16-bit MCU, S12Z core, 64KB Flash, 32MHz, -40/+85degC, Automotive Qualified, QFP 144

Datasheet

300In Stock

$16.34

$12.41

$11.90

$9.35

View

Min.: 1
Mult.: 1

S12Z

64 kB

10 bit

104 I/O

5 V

18 V

SMD/SMT

16 bit

- 40 C

+ 105 C

S12ZVH

AEC-Q100

Tray

16-bit Microcontrollers - MCU MagniV 16-bit MCU, S12Z core, 32KB Flash, 50MHz, -40/+150degC, Automotive Grade, LQFP 48

S912ZVML31F1WKF
NXP Semiconductors
1: $9.24
1,250In Stock

Mfr. Part #
S912ZVML31F1WKF

Mouser Part #
841-S912ZVML31F1WKF

NXP Semiconductors

16-bit Microcontrollers - MCU MagniV 16-bit MCU, S12Z core, 32KB Flash, 50MHz, -40/+150degC, Automotive Grade, LQFP 48

Learn More

Datasheet

1,250In Stock

$9.24

$7.18

$6.67

$6.10

View

Min.: 1
Mult.: 1

S12Z

32 kB

4 kB

QFP-48

50 MHz

12 bit

1.72 V

1.98 V

SMD/SMT

16 bit

- 40 C

+ 150 C

S12ZVM

AEC-Q100

Tray

16-bit Microcontrollers - MCU 16-bit MCU, S12 core, 64KB Flash, 32MHz, -40/+85degC, Automotive Qualified, QFP 100

S9S12HY64J0CLL
NXP Semiconductors
1: $7.87
899In Stock

Mfr. Part #
S9S12HY64J0CLL

Mouser Part #
841-S9S12HY64J0CLL

NXP Semiconductors

16-bit Microcontrollers - MCU 16-bit MCU, S12 core, 64KB Flash, 32MHz, -40/+85degC, Automotive Qualified, QFP 100

Datasheet

899In Stock

$7.87

$7.35

$7.34

Min.: 1
Mult.: 1

S12

64 kB

4 kB

QFP-100

64 MHz

10 bit

80 I/O

4.5 V

5.5 V

SMD/SMT

16 bit

- 40 C

+ 85 C

S12HY

AEC-Q100

Tray

16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G13 192K 80LQFP -40 to 85 C

R5F100MHAFA#10
Renesas Electronics
1: $3.80
720In Stock

Mfr. Part #
R5F100MHAFA#10

Mouser Part #
968-R5F100MHAFA#10

Renesas Electronics

16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G13 192K 80LQFP -40 to 85 C

Learn More

Datasheet

720In Stock

$3.80

$2.87

$2.64

$2.39

View

Min.: 1
Mult.: 1

RL78

192 kB

16 kB

LQFP-80

32 MHz

8 bit/10 bit

74 I/O

1.6 V

5.5 V

SMD/SMT

16 bit

- 40 C

+ 85 C

RL78/G13

Tray

16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G13 192K 80LFQFP -40 to 85 C

R5F100MHAFB#50
Renesas Electronics
1: $6.78
944In Stock

Mfr. Part #
R5F100MHAFB#50

Mouser Part #
968-R5F100MHAFB#50

Renesas Electronics

16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G13 192K 80LFQFP -40 to 85 C

Learn More

Datasheet

944In Stock

Cut Tape

$6.78

$4.98

$4.64

$4.08

Reel

$3.01

View

Min.: 1
Mult.: 1

: 1,000

RL78

512 kB

32 kB

LFQFP-80

32 MHz

8 bit, 10 bit

74 I/O

1.6 V

5.5 V

SMD/SMT

16 bit

- 40 C

+ 85 C

RL78/G13

Reel, Cut Tape

16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G14 32K 30LSSOP -40 to 85 C

R5F104ACASP#10
Renesas Electronics
1: $2.46
1,494In Stock

Mfr. Part #
R5F104ACASP#10

Mouser Part #
968-R5F104ACASP#10

Renesas Electronics

16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G14 32K 30LSSOP -40 to 85 C

Learn More

Datasheet

1,494In Stock

$2.46

$1.69

$1.50

$1.33

View

Min.: 1
Mult.: 1

RL78

32 kB

4 kB

32 MHz

8 bit/10 bit

26 I/O

1.6 V

5.5 V

SMD/SMT

16 bit

- 40 C

+ 85 C

RL78/G14

Tray

16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G14 96K 32LQFP -40 to 85 C

R5F104BFAFP#10
Renesas Electronics
1: $2.30
1,865In Stock

Mfr. Part #
R5F104BFAFP#10

Mouser Part #
968-R5F104BFAFP#10

Renesas Electronics

16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G14 96K 32LQFP -40 to 85 C

Learn More

Datasheet

1,865In Stock

$2.30

$1.71

$1.56

$1.40

View

Min.: 1
Mult.: 1

RL78/G14

Tray

16-bit Microcontrollers - MCU 16BIT MCU RL78/L13 96K 64LFQFP -40/+105C

R5F10WLFGFB#10
Renesas Electronics
1: $4.50
1,026In Stock

Mfr. Part #
R5F10WLFGFB#10

Mouser Part #
968-R5F10WLFGFB#10

Renesas Electronics

16-bit Microcontrollers - MCU 16BIT MCU RL78/L13 96K 64LFQFP -40/+105C

Learn More

Datasheet

1,026In Stock

$4.50

$2.98

$2.72

$2.31

View

Min.: 1
Mult.: 1

RL78/L13

Tray

16-bit Microcontrollers - MCU 128KB FL 16KB RAM 60MHz 44Pin

PIC24EP128MC204-I/ML
Microchip Technology
1: $4.08
484In Stock

Mfr. Part #
PIC24EP128MC204-I/ML

Mouser Part #
579-24EP128MC204IML

Microchip Technology

16-bit Microcontrollers - MCU 128KB FL 16KB RAM 60MHz 44Pin

Learn More

Datasheet

484In Stock

$4.08

$3.82

Min.: 1
Mult.: 1

PIC24E

128 kB

16 kB

QFN-44

60 MHz

10 bit, 12 bit

35 I/O

3 V

3.6 V

SMD/SMT

16 bit

- 40 C

+ 85 C

PIC24EPxxxMC20x

AEC-Q100

Tube

16-bit Microcontrollers - MCU 16b 16 MIPS 32KB Flash 8192b RAM

PIC24FJ32GA002-E/SS
Microchip Technology
1: $3.65
235In Stock

Mfr. Part #
PIC24FJ32GA002-E/SS

Mouser Part #
579-PIC24FJ32GA00

Microchip Technology

16-bit Microcontrollers - MCU 16b 16 MIPS 32KB Flash 8192b RAM

Learn More

Datasheet

235In Stock

$3.65

$3.34

$3.04

Min.: 1
Mult.: 1

PIC24F

32 kB

8 kB

SSOP-28

32 MHz

10 bit

21 I/O

2 V

3.6 V

SMD/SMT

16 bit

- 40 C

+ 125 C

PIC24FJxxGA00x

AEC-Q100

Tube

16-bit Microcontrollers - MCU 32KB FLSH 4096Bs RAM 16B nanoWatt

PIC24FJ32GA002T-I/SS
Microchip Technology
1: $3.39
1,830In Stock

Mfr. Part #
PIC24FJ32GA002T-I/SS

Mouser Part #
579-PIC24FJ32GA002TI

Microchip Technology

16-bit Microcontrollers - MCU 32KB FLSH 4096Bs RAM 16B nanoWatt

Learn More

Datasheet

1,830In Stock

Cut Tape

$3.39

$3.29

$3.19

$2.80

Reel

$2.80

MouseReel Available

Min.: 1
Mult.: 1

: 2,100

PIC24F

32 kB

8 kB

SSOP-28

32 MHz

10 bit

21 I/O

2 V

3.6 V

SMD/SMT

16 bit

- 40 C

+ 85 C

PIC24FJxxGA00x

AEC-Q100

Reel, Cut Tape, MouseReel

16-bit Microcontrollers - MCU 16B MCU 44LD64KB DMA 40MIPS

PIC24HJ64GP204-I/ML
Microchip Technology
1: $6.28
135In Stock

Mfr. Part #
PIC24HJ64GP204-I/ML

Mouser Part #
579-PIC24H64GP204IML

Microchip Technology

16-bit Microcontrollers - MCU 16B MCU 44LD64KB DMA 40MIPS

Learn More

Datasheet

135In Stock

$6.28

$5.76

$5.23

Min.: 1
Mult.: 1

PIC24H

64 kB

8 kB

QFN-44

40 MHz

10 bit, 12 bit

35 I/O

3 V

3.6 V

SMD/SMT

16 bit

- 40 C

+ 85 C

PIC24HJxxxGP20x

AEC-Q100

Tube

16-bit Microcontrollers - MCU 16B MCU 44LD64KB DMA 40MIPS

PIC24HJ64GP504-I/ML
Microchip Technology
1: $6.92
494In Stock

Mfr. Part #
PIC24HJ64GP504-I/ML

Mouser Part #
579-PIC24H64GP504IML

Microchip Technology

16-bit Microcontrollers - MCU 16B MCU 44LD64KB DMA 40MIPS

Learn More

Datasheet

494In Stock

$6.92

$6.33

$5.74

Min.: 1
Mult.: 1

PIC24H

64 kB

8 kB

QFN-44

40 MHz

10 bit, 12 bit

35 I/O

3 V

3.6 V

SMD/SMT

16 bit

- 40 C

+ 85 C

PIC24HJxxxGPx04

AEC-Q100

Tube

16-bit Microcontrollers - MCU 4kB Flash 256B RAM 1 0bit ADC + 1 USART A 595-430F1222IRHBR

MSP430F1222IRHBT
Texas Instruments
1: $7.58
195In Stock

Mfr. Part #
MSP430F1222IRHBT

Mouser Part #
595-430F1222IRHBT

Texas Instruments

16-bit Microcontrollers - MCU 4kB Flash 256B RAM 1 0bit ADC + 1 USART A 595-430F1222IRHBR

Learn More

Datasheet

195In Stock

Cut Tape

$7.58

$5.85

$5.42

$4.95

Reel

$4.72

View

MouseReel Available

Min.: 1
Mult.: 1

: 250

MSP430

4 kB

256 B

VQFN-32

8 MHz

10 bit

22 I/O

1.8 V

3.6 V

SMD/SMT

16 bit

- 40 C

+ 85 C

MSP430F1222

Reel, Cut Tape, MouseReel

16-bit Microcontrollers - MCU 32 kB Flash 1KB RAM 2 USART + HW multplr A 595-430F1471IPM

MSP430F1471IPMR
Texas Instruments
1: $15.45
488In Stock

Mfr. Part #
MSP430F1471IPMR

Mouser Part #
595-430F1471IPMR

Texas Instruments

16-bit Microcontrollers - MCU 32 kB Flash 1KB RAM 2 USART + HW multplr A 595-430F1471IPM

Learn More

Datasheet

488In Stock

Cut Tape

$15.45

$12.21

$11.40

$10.52

View

Reel

$9.59

MouseReel Available

Min.: 1
Mult.: 1

: 1,000

MSP430

32 kB

1 kB

LQFP-64

8 MHz

12 bit

48 I/O

1.8 V

3.6 V

SMD/SMT

16 bit

- 40 C

+ 85 C

MSP430F1471

Reel, Cut Tape, MouseReel

16-bit Microcontrollers - MCU for Elec Flow Meters A 595-430FW427IPM A A 595-430FW427IPM

MSP430FW427IPMR
Texas Instruments
1: $9.49
970In Stock

Mfr. Part #
MSP430FW427IPMR

Mouser Part #
595-430FW427IPMR

Texas Instruments

16-bit Microcontrollers - MCU for Elec Flow Meters A 595-430FW427IPM A A 595-430FW427IPM

Learn More

Datasheet

970In Stock

Cut Tape

$9.49

$9.01

$8.90

$8.58

View

Reel

$7.47

MouseReel Available

Min.: 1
Mult.: 1

: 1,000

MSP430

32 kB

1 kB

LQFP-64

16 MHz

No ADC

48 I/O

1.8 V

3.6 V

SMD/SMT

16 bit

- 40 C

+ 85 C

MSP430FW427

Reel, Cut Tape, MouseReel

16-bit Microcontrollers - MCU 16 MHz MCU with 48KB Flash 2KB SRAM 10 A A 595-M430G2855IRHA40R

MSP430G2855IRHA40T
Texas Instruments
1: $5.94
302In Stock

Mfr. Part #
MSP430G2855IRHA40T

Mouser Part #
595-M430G2855IRHA40T

Texas Instruments

16-bit Microcontrollers - MCU 16 MHz MCU with 48KB Flash 2KB SRAM 10 A A 595-M430G2855IRHA40R

Learn More

Datasheet

302In Stock

Cut Tape

$5.94

$4.55

$3.99

$3.81

Reel

$3.62

View

MouseReel Available

Min.: 1
Mult.: 1

: 250

MSP430

48 kB

4 kB

VQFN-40

16 MHz

10 bit

32 I/O

SMD/SMT

16 bit

- 40 C

+ 85 C

MSP430G2855

Reel, Cut Tape, MouseReel

16-bit Microcontrollers - MCU 16B MCU A 595-MSP430 AFE221IPW A 595-MSP A 595-MSP430AFE221IPW

MSP430AFE221IPWR
Texas Instruments
1: $4.12
1,951In Stock

Mfr. Part #
MSP430AFE221IPWR

Mouser Part #
595-MSP430AFE221IPWR

Texas Instruments

16-bit Microcontrollers - MCU 16B MCU A 595-MSP430 AFE221IPW A 595-MSP A 595-MSP430AFE221IPW

Learn More

Datasheet

1,951In Stock

Cut Tape

$4.12

$3.94

$3.86

$3.69

View

Reel

$2.68

MouseReel Available

Min.: 1
Mult.: 1

: 2,000

MSP430

4 kB

256 B

TSSOP-24

16 MHz

24 bit

11 I/O

1.8 V

3.6 V

SMD/SMT

16 bit

- 40 C

+ 85 C

MSP430AFE221

Reel, Cut Tape, MouseReel

16-bit Microcontrollers - MCU 16B MCU A 595-MSP430 AFE231IPW A 595-MSP A 595-MSP430AFE231IPW

MSP430AFE231IPWR
Texas Instruments
1: $6.84
1,552In Stock

Mfr. Part #
MSP430AFE231IPWR

Mouser Part #
595-MSP430AFE231IPWR

Texas Instruments

16-bit Microcontrollers - MCU 16B MCU A 595-MSP430 AFE231IPW A 595-MSP A 595-MSP430AFE231IPW

Learn More

Datasheet

1,552In Stock

Cut Tape

$6.84

$5.03

$4.68

$4.12

Reel

$2.92

View

MouseReel Available

Min.: 1
Mult.: 1

: 2,000

MSP430

8 kB

512 B

TSSOP-24

16 MHz

24 bit

11 I/O

1.8 V

3.6 V

SMD/SMT

16 bit

- 40 C

+ 85 C

MSP430AFE231

Reel, Cut Tape, MouseReel

16-bit Microcontrollers - MCU 16-bit Ult-Lo-Pwr 2k B Flash 128B RAM A A 595-MSP430F2111IPWR

MSP430F2111IPW
Texas Instruments
1: $3.13
508In Stock

Mfr. Part #
MSP430F2111IPW

Mouser Part #
595-MSP430F2111IPW

Texas Instruments

16-bit Microcontrollers - MCU 16-bit Ult-Lo-Pwr 2k B Flash 128B RAM A A 595-MSP430F2111IPWR

Learn More

Datasheet

508In Stock

$3.13

$2.34

$1.98

$1.88

View

Min.: 1
Mult.: 1

MSP430

2 kB

128 B

TSSOP-20

16 MHz

No ADC

16 I/O

1.8 V

3.6 V

SMD/SMT

16 bit

- 40 C

+ 105 C

MSP430F2111

Tube

16-bit Microcontrollers - MCU 16-bit Ult-Lo-Pwr 4k B Flash 256B RAM A A 595-MSP430F2121IPWR

MSP430F2121IPW
Texas Instruments
1: $3.21
490In Stock

Mfr. Part #
MSP430F2121IPW

Mouser Part #
595-MSP430F2121IPW

Texas Instruments

16-bit Microcontrollers - MCU 16-bit Ult-Lo-Pwr 4k B Flash 256B RAM A A 595-MSP430F2121IPWR

Learn More

Datasheet

490In Stock

$3.21

$2.41

$2.04

$1.94

View

Min.: 1
Mult.: 1

MSP430

4 kB

256 B

TSSOP-20

16 MHz

No ADC

16 I/O

1.8 V

3.6 V

SMD/SMT

16 bit

- 40 C

+ 105 C

MSP430F2121

Tube

16-bit Microcontrollers - MCU 16B Ultra-Lo-Pwr Mic rocntrlr A 595-MSP4 A 595-MSP430F2132TPW

MSP430F2132TPWR
Texas Instruments
1: $6.05
331In Stock
2,000Expected 10/22/2026

Mfr. Part #
MSP430F2132TPWR

Mouser Part #
595-MSP430F2132TPWR

Texas Instruments

16-bit Microcontrollers - MCU 16B Ultra-Lo-Pwr Mic rocntrlr A 595-MSP4 A 595-MSP430F2132TPW

Learn More

Datasheet

331In Stock

2,000Expected 10/22/2026

Cut Tape

$6.05

$4.64

$4.28

$3.89

View

Reel

$3.35

MouseReel Available

Min.: 1
Mult.: 1

: 2,000

MSP430

8 kB

512 B

TSSOP-28

16 MHz

10 bit

24 I/O

1.8 V

3.6 V

SMD/SMT

16 bit

- 40 C

+ 105 C

MSP430F2132

Reel, Cut Tape, MouseReel

16-bit Microcontrollers - MCU

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6 I/O
7 I/O
8 I/O
10 I/O
11 I/O
12 I/O
13 I/O
14 I/O
15 I/O
16 I/O
17 I/O
18 I/O
19 I/O
20 I/O
21 I/O
22 I/O
23 I/O
24 I/O

900 mV
1.2 V
1.6 V
1.67 V
1.7 V
1.71 V
1.72 V
1.8 V
1.98 V
2 V
2.2 V
2.25 V
2.35 V
2.4 V
2.5 V
2.7 V
2.97 V
3 V
3.15 V
3.3 V

68HC912D60A
78K0R/Ix3
78K0R/Kx3
78K0R/Kx3-L
CP3SP33
DS4830
H8S/2100
H8S/2400
IA186ER, IA188ER
M16C/28
M16C/56
M16C/62P
M16C/63
M16C/64
M16C/64A
M16C/65
M16C/65C
M16C/6C
MAX1464
MAX28200